ANALISI CHIMICO FARMACEUTICA SAVELLI PDF
Results 1 – 8 Download Chimico farmaceutica savelli bruno and more books of the same author and others for free. a) F. SAVELLI, O. BRUNO: Analisi chimico Farmaceutica – Editore c) G.C. PORRETTA: Analisi quantitativa di composti farmaceutici – CISU. 5 a Ed. ETS Editrice, Pisa F. Savelli, O. Bruno. Analisi Chimico Farmaceutica – Piccin, Padova, A. Carta, M. G. Mamolo, F. Novelli.
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If the written examination results positive, the final mark will be modified, but not averaged, by taking into consideration also the evaluation of the laboratory reports. The final target is to set a rational basis for the study of the systematic medicinal chemistry. ETS Editrice, Pisa The student who successfully completes the course will be able to demonstrate a solid knowledge of the main methodologies involved in an analytical process aimed at identifying the identity and the purity of unknown compounds and, in particular, of compounds included in the European Pharmacopoeia.
Target identification and validation, lead identification.
Francesco Savelli ( of Analisi chimico farmaceutica)
Determinazione di alcune costanti fisiche. Initially the students will be trained to understand the general nature of their analytes organic, inorganic, mixed.
Individuazione dell’azoto, zolfo, alogeni, fosforo, arsenico. Filtration and recrystallization of an organic reaction product, with TLC control. Esercitazioni individuali in laboratorio.
Prodrugs and bioprecursors strategy. Lipophilicity definitions and lipophilicity scales. Farmacocinetica e Farmacodinamica su Basi Chimico-Fisiche.
Ssvelli della struttura aromatica; ricerca dell’insaturazione attiva; acidi carbossilici; acidi solfonici; a-amminoacidi; esteri; aldeidi e. Salta alla navigazione Strumenti personali. Natura di un campione analitico. Stoichiometric calculations, mass and volume measurements. Laboratory class for in total 24 hours, divided into 6 sessions.
General Medicinal Chemistry part. The course provides notions on the main procedures to be followed during a qualitative analysis. Theorical basis of chromatographic separations, and TLC laboratory practice with samples of different compounds mixtures. Learning assessment procedures Written examination and laboratory reports.
Main tarmaceutica phases 1 and 2 transformations.
GENERAL PHARMACEUTICAL CHEMISTRY AND LABORATORY
Moreover, students will be engaged in some basic operations of organic chemistry, including purification and quality control of a reaction product. The drug discovery process. Assessment criteria of skills. Sostanze organiche, inorganiche, a composizione mista; sostanze pure, impure, in miscela; comportamento delle Sostanze al calore.
Assessment criteria of knowledge. Lead compound optimisation, candidate compound selection, pharmacophore.
Interaction of drugs with receptors full, partial or inverse agonists, antagonistsenzymes reversible, irreversible, allosteric inhibitors and other biological targets. Identificazione sistematica di composti organici – Editoriale Grasso, Bologna, Vogel’s textbook of practical organic chemistry – 5th Ed.
Università di Pisa – Valutazione della didattica e iscrizione agli esami
Ionization rate, water solubility, definition and calculation of logP and logD. Riconoscimento di alcune sostanze iscritte nella Farmacopea Europea. Manuale di chimica farmaceutica. Assessment criteria of behaviors.
Caratterizzazione di composti organici mediante derivati cristallini. Electrical conductivity of solutions and laws of conductivity. Guida pratica al riconoscimento delle sostanze iscritte nella V edizione della Farmacopea Europea. Drug distribution, acid-base fqrmaceutica. Chimica farmaceutica generale con laboratorio. Riconoscimento di sostanze organiche e di farmaci metallo-organici e organici inclusi nella Farmacopea Europea.